Anti-Spike Mucosal IgA Protection Against SARS-CoV-2 Infection Omicron |  NEJM

Anti-Spike Mucosal IgA Protection Against SARS-CoV-2 Infection Omicron | NEJM

For the editor: Mucosal IgA can provide immunity against respiratory viruses.1 Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulates mucosal IgA responses,2 and neutralizing IgA, including neutralizing IgA against the B.1.1.529 (omicron) variant of SARS-CoV-2, have been detected after infection with wild-type SARS-CoV-2.3 However, the potential role of mucosal IgA in protecting against …

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